Traditionally once removed from the animal, tissue is immediately cooled to close to +4° C to lower the oxygen demand and prevent anoxia. However, we have just developed the 7611A due to the paper by Huang S & Uusisaari MY (2013), who demonstrated that slicing at physiological temperature improves the viability and connectivity of the neurons in the slice.

Temperature Control above shown with bath and mount (not included).

We only recommend the 7611A for use with the 7000smz-2, as this technique has only be shown to be effective if the Z-axis deflection is calibrated to >0.4µm, and the optimal calibrated Z-axis of the 5100mz is 2 ± 0.1µm. The 7000smz-2 Vibrotome has class leading (when correctly calibrated) Z-axis deflection of ≤1 ± 0.1µm at the whole range of speeds and amplitudes of vibration.

Specifications:

  • Display Resolution: 0.1° C
  • Temperature Accuracy: +/- 1° C
  • Temperature Range: +10-50° C**
  • Voltage Requirements: 230V 50Hz or 115V 60Hz
  • Power Rating: 60W
  • Inlet Fuse Rating: T1.25A

**Note: The actual temperatures achievable will be dependent upon the solutions used and local temperature conditions