LumiCycle In Vivo

LumiCycle In Vivo is designed to record PER-LUC light emissions from awake behaving animals placed in a standard mouse cage and infused with luciferin analogs.

For over a decade, it has been possible to record PER-LUC light emission from isolated tissues and cells. As methods and signals improve, it is now possible to record light emission from intact, behaving animals, opening up a wide range of experiments on the interactions among the clocks in different organs operating in their natural environment. LumiCycle In Vivo is a simple, robust apparatus for recording luminescence from intact animals, while simultaneously recording activity, monitoring light, temperature, and humidity within the chamber, and controlling the lights in infinitely programmable skeleton schedules.